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KMID : 0366219900250010267
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Korean Journal of Hematology
1990 Volume.25 No. 1 p.267 ~ p.272
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Cis-AB Bloods Found in Four Korean families
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김명한/Myung Han Kim
김원배/강영복/이동화/강득용/Won Bae Kim/Young Bok Kang/Dong Wha Lee/Duk Yong Kang
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Abstract
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AB blood group is determined by A and B genes located on each chromosomes which
are inherited from parents. But unusual inheritance of A and B genes on the same
chromosome has been reported as cis-AB. We found 11 cases of cis-AB in four families
during last 2 years with family studies.
Yamaguchi suggested the three phenotypes of the cis-AB and their probable
genotypes.
We propose that there is a possible explanation of inheritance of genotypes for cis-AB
blood, A1B3, A2B as well as
A2B3 on same chromosome produced by chromosomal
crossing over at the stage of differentiation or Proliferation of the cells and their
mosaicism is possible.
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KEYWORD
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